More Possible Uses:
CUT CHOLESTEROL: Studies have shown levan to effectively lower cholesterol (Yamamoto, Kang a, Kang b). Although most of this work has been done in rats, one recent presentation included data from a small group of women whose diet was supplemented with levan (Kang b). The levan diet was credited with controlling both cholesterol levels and weight.
There are many powerful cholesterol-lowering drugs available, but there are growing concerns about their use for extended periods of time. The FDA has recently rejected over-the-counter sales of a cholesterol-lowering statin. Safety was a major concern but the idea was proposed because only a small fraction of people with high cholesterol levels is on medication. The argument was if a suitable drug were available over-the-counter, far more people would be taking it. This would appear to be a possible niche for levan as a dietary supplement. Our levan does not have FDA approval so we are looking for a larger company interested in taking on the entire project.
Yamamoto Y, Takahashi Y, Kawano M, Iizuka M, Matsumoto T, Sacki S, Yamaguchi H. In vitro digestibility and fermentability of levan and its hypocholesterolemic effects in rats. The Journal of Nutritional Biochemistry 10:13-18 (1999).
Kang S, Hong K, Jang K, Kim S, Lee K, Chang B, Kim C, Choue R. Anti-obesity and hypolipidemic effects of dietary levan in high fat diet-induced obese rats. Journal of Microbiology and Biotechnology 14(4): 796-804 (2004). (a)
Kang S, Jang K, Lee J, Chang B, Lim Y. The effects of fructose polymer, levan, on the body fat contents and serum lipid profiles of Korean women. Presented at Experimental Biology 2004, Washington, DC (2004). (b)