Montana Polysaccharides Corp.

MSDS for Levan

1. IDENTIFICATION OF SUBSTANCE AND COMPANY INFORMATION

Product name: Levan
Trade name: Levana™
Synonyms: ß-2,6 polyfructose with ß-2,1 bonding at branches; ß-2,6 fructan

Supplier:
Montana Polysaccharides Corp.
119 Cathcart Circle
Winnsboro, SC 29180-1010, USA
Phone and Fax: 803-815-0630
Email: joan@polysaccharides.us
Website: www.polysaccharides.us

Manufacturer Main Office:
Kaley's Holdings
Shanghai Cathay Biotechnology
Building 5#
1690 Cailun Road
Zhangjiang Hightech Park, 201203 Shanghai, PR China
Phone: +86-21-50801916
Fax: +86-21-50801386
Website: www.cathaybiotech.com

Manufacturing Location:
Shandong Cathay Lineng Biotechnology Co.
Ltd High & New Tech Industries
Development Zone, Jining, Shandong 272073, PR China
Phone: +86-21-50801916


2. COMPOSITION

Identification: Levan, CAS # 9013-95-0. INCI name is levan. The EINECS number for fructose is 200-333-3.
Levan is a polymer of fructose. Polymers made from EINECS-listed monomers are exempt from notification.
Source: Bacillus sp.


3. HAZARDS IDENTIFICATION

This compound is considered to be of low hazard by ingestion or contact.
Exercise appropriate procedures to minimize any potential hazard.
BCOP and CAMVA indicate levan in not an ocular irritant.
However, if a solution of levan contacts the eye, it should be removed by flushing with water.

Ensure that atmospheric dust levels are kept to a minimum.
Fine powder may present possibility of dust explosion.
Long term exposure to excessive levels of any dust can lead to respiratory problems.
Levan is water soluble so low levels will be dissolved fairly rapidly.


4. FIRST AID MEASURES

Skin contact: Usually no problems arise. Cleanse with mild soap and water.
Eye contact: In case of contact with eyes, flush with water.
Inhalation: Avoid inhalation of dust.
Ingestion: No measures recommended.


5. FIRE FIGHTING MEASURES

Flammability: Flammable in presence of open flame. Melts and chars at high temperatures.
Extinguishing media: Water or appropriate foam.
Explosion potential: Fine powder may present possibility of dust explosion.
Flash point: Not available


6. ACCIDENTAL RELEASE MEASURES

Personal precautions: Not classified as hazardous.
Environmental precautions: Levan will biodegrade to fructose. Small amounts are not hazardous. Avoid creating dust.
Use caution when removing with water since surfaces could be a slipping hazard.


7. HANDLING AND STORAGE

Dry form: Store in cool, dry place in tightly closed container. Avoid generation of dust.
Wet form: Take measures to avoid microbial contamination.


8. EXPOSURE CONTROLS AND PERSONAL PROTECTION

Avoid inhalation of dust. Use only in area with appropriate exhaust ventilation.
Levan has adhesive properties and will stick to skin but may be removed with water. HRIPT shows no irritation.


9. PHYSICAL/CHEMICAL PROPERTIES

Appearance: White to off white. Transparent in thin film form. Dry form available in flakes or powder.
May be suspended in water to form slightly hazy to cloudy solution.
Solubility and viscosity: "Soluble" in water or water plus a water-miscible solvent.
At a molecular weight of over 2 million, this levan is not truly water soluble. Rather levan forms a suspension that does not readily settle out. Flakes require several hours to "dissolve" in cold water. Powdered levan will appear to solubilize more rapidly.
Levan is not soluble or degraded in jet fuel, d-limonene, methylethylketone or toluene after 48 hours.
Levan is soluble in DMSO; no other organic solvents have been identified.
Solutions up to 20% solids have a low viscosity; 20-40% solids form a thin paste; 50% solids make a thick gum.

Melting point: Melts with decomposition at 225°C (437°F).

Odor: None.

Dust: If levan is ground to a powder, appropriate safety measures should be taken as for any material creating dust, to avoid the possibility of explosion.

Molecular weight: Over 2 million Daltons.

Specific gravity: 1.4


10. STABILITY

Stable in a cool, dry place. Degrades in strong acid. Avoid moisture which could lead to microbial contamination.


11. TOXICOLOGICAL INFORMATION

The oral LD50 is unknown. (In a study on Swiss albino mice, levan doses up to 3,200 mg/kg were given without any sign of toxicity.
Calazans G, Lopes C, Lima R, de Franca F. Biotechnology Letters 19(1): 19-20 (1997).

Levan is non-cytotoxic, meeting the requirements of the Agar Diffusion Test. Endotoxin by LAL testing is 10-20 EU/ml.
By way of comparison, municipal water systems usually contain 10-100 EU/ml (J Cooper, editor, LAL Times, Vol 5, No 2 (1998).


12. ECOLOGICAL INFORMATION

Levan is biodegradable and water "soluble". It will degrade to fructose which is not hazardous in small quantities.


13. DISPOSAL CONSIDERATIONS

Discharge, treatment or disposal may be subject to federal, state or local laws.


14. TRANSPORT INFORMATION

Levan is not listed as a hazardous material by the US DOT, Office of Hazardous Materials Safety.


15. REGULATIONS

TSCA application submitted.


16. OTHER INFORMATION

Limitation of Liability.
THE MATERIALS ARE EXPERIMENTAL IN NATURE AND MAY HAVE HAZARDOUS PROPERTIES.
IN NO EVENT SHALL MONTANA POLYSACCHARIDES CORP. OR KALEY'S HOLDINGS BE LIABLE FOR ANY USE OF THE MATERIAL BY THE RECIPIENT, OR FOR ANY LOSS, CLAIM, DAMAGE OR LIABILITY OF ANY KIND, WHICH MAY ARISE FROM OR IN CONNECTION WITH THIS INFORMATION OR FROM THE USE, HANDLING OR STORAGE OF THE MATERIAL, WHETHER DIRECT, INDIRECT, OR CONSEQUENTIAL, OR FOR ANY CLAIM BY ANY THIRD PARTY.
THE FOREGOING LIMITATIONS APPLY REGARDLESS OF THE CAUSES OR CIRCUMSTANCES GIVING RISE TO SUCH LOSS, DAMAGE OR LIABILITY, EVEN IF SUCH LOSS, DAMAGE OR LIABILITY IS BASED ON NEGLIGENCE OR OTHER TORTS OR BREACH OF CONTRACT.

Disclaimer: This information is provided without warranty but is accurate to the best of our knowledge.
Last updated: 7/07

Montana Polysaccharides :: (803) 815-0630 :: joan@polysaccharides.us